10 Best Glucosamine Supplements Tested
Our bodies produce a natural shock absorber and lubricant that helps us live active lives without experiencing contstant pain from friction. This natural shock absorber is glucosamine. Glucosamine is an amino sugar that is naturally found in our cartilage. Our bodies need glucosamine to synthesize protein and lipids to form important tissues, like cartilage, with the help of compounds like aggrecan and proteoglycans.
It is an important component of our joints, tendons, and ligaments, and helps to form the fluids that provide lubrication to our joints. And as if glucosamine didn’t do enough for us already, it also contributes to our microbiome health by forming connective tissues that make up the digestive tract and help our immune system function at its highest level.
10 Best Glucosamine Supplements
1. Schiff Move Free Advanced
Move Free Advanced is specially formulated to support the five signs of joint health: mobility, comfort, strength, flexibility, and lubrication. Users report that within one month of consistently taking the recommended dose of Move Free Advanced, they felt a significant reduction in joint pain, especially in their hips.
Move Free Advanced glucosamine supplement contains: 1500 mg of glucosamine which supports the formation of cartilage and everyday mobility and flexibility, 200 mg of chondroitin to support joint strength, cushioning, and lubrication; 200 mg of a mineral compound called Uniflex that Move Free says will lessen pain within 2 weeks, 3.3 mg of hyaluronic acid, which helps support joint lubrication, and 1500 mg of MSM which is a source of sulfur related to collagen production.
Move Free Advanced is about the average price for a glucosamine supplement.
- Quick relief from pain
- Includes compounds that occur naturally in the body
- Must take 3 pills per day
2. Doctor’s Best Glucosamine
Users of Doctor’s Best Glucosamine say that this supplement starts to take affect after two weeks of consistent use. They also say that you must take the whole two-pill dose, or else you will begin feeling pain again almost immediately.
A two-capsule dose of Doctor’s Best Glucosamine contains 750 mg of glucosamine sulfate, 600 mg of chondroitin sulfate, and 500 mg of MSM. This combination of ingredients has been shown to increase cartilage production and lubrication around joints, and decrease joint pain. Doctor’s Best Glucosamine is the only glucosamine supplement to contain OptiMSM, a specially-formulated blend of MSM created by Bergstrom Nutrition, which has been scientifically proven to improve joint, skin, and immune health.
Doctor’s Best Glucosamine is a lower-priced glucosamine supplement.
- GMO- and gluten-free
- Pain returns immediately upon not taking supplement
3. Kirkland Signature Extra Strength Glucosamine
Two tablets of this glucosamine supplement will help your body produce extra collagen, which is an important component of your joints and connective tissue. Users reported that after a few weeks of use, joint pain, especially in the knees, was reduced. However, some users also reported having to discontinue use of this product due to increases in ocular pressure, which can lead to eye problems like glaucoma and vision loss.
Due to its wholesale size, this is one of the least expensive glucosamine supplements on the market.
- Low price
- Reported reduction in knee pain
- May cause increases in ocular pressure
4. VitaBreeze Triple Strength
VitaBreeze guarantees that four of their gelatin-free Veggie Capsules will provide you with joint pain relief in 60 days, or they will refund your purchase. Users report greatly increased mobility, decreased pain, and that taking this supplement has nearly eliminated the use of OTC pain relievers from their joint pain management routine.
Each dose of VitaBreeze Triple Strength is 4 capsules, and it is recommended that you take two, 2-pill doses daily. Each dose of this glucosamine supplement contains 1500 mg glucosamine, 1000 mg chondroitin, 600 mg MSM, and 300 mg turmeric.
This is a higher priced glucosamine supplement.
- Contains natural antioxidant/anti inflammatory turmeric
5. Zenwise Labs Joint Support Pro-Mobility Formula
After 28 days of taking this glucosamine supplement, one user with severe joint problems reporting comfort sleeping at night, and that there was no longer cracking or popping in the knees or shoulders.
Two tablets of Zenwise Labs Joint Support Pro-Mobility Formula will give you 1500 mg of glucosamine, 1200 mg of chondroitin, and 1000 mg of MSM. This combination of medicines promotes joint and muscle flexibility as well as joint health.
This glucosamine supplement is a little pricier than most others.
- Takes effect in less than one month
- Supplemental ingredients are natural
- Higher price than most other supplements
6. Wellesse Joint Movement Glucosamine
Users report that Wellesse Joint Movement Glucosamine doesn’t taste terrible, but it is overly sweetened with artificial sweeteners.
One ounce per day, or tablespoons, of this glucosamine supplement will provide you with 2000 mg of glucosamine, 1200 mg of chondroitin, 500 mg of MSM, and 10 mg of hyaluronic acid. This liquid formula is made with no artificial ingredients or flavors.
This glucosamine supplement is priced a little above average.
- High concentration of glucosamine
- Artificially sweetened taste
7. Universal Nutrition Animal Flex
Users report some relief of joint pain and discomfort, but they also report side effects such as headaches, sinus pressure, and a racing heart.
One serving of Animal Flex is one packet, and it must be taken with a meal. Animal Flex glucosamine supplement has three “Complexes”: Joint Construction, Joint Lubrication, and Joint Support. The Joint Construction Complex contains glucosamine, MSM, and chondroitin. The Joint Lubrication Complex contains flaxseed oil, a cetyl myristoleate proprietary blend, and hyaluronic acid. The Joint Support Complex contains ginger, turmeric, boswellic acid, quercetin, and bromelain.
Animal Flex is a slightly higher priced glucosamine supplement.
- Offers joint construction, support and lubrication
- Potential side effects
8. Schiff Glucosamine
Users report quick results with joint pain in hips and knees, and Schiff Glucosamine Plus MSM has even provided relief for pets.
Three tablets once daily of this glucosamine supplement contain 1500 mg of glucosamine, 1500 mg of MSM, and 3 mg of hyaluronic acid. Together, these ingredients help relieve joint discomfort, promote lubrication, and increase cushioning. There is no chondroitin in this formula.
This glucosamine supplement is priced slightly lower than others.
- Quick relief
- Does not contain chondroitin
9. NOW Foods Glucosamine
Users report that this product did help their joint pain, but the dosage had to be adjusted because it contains lesser concentrations of glucosamine, chondroitin, and MSM than some other glucosamine supplement formulas. It was recommended to users to calculate a new dosage based on their body weight.
A three-capsule dose of NOW Foods Glucoosamine contains 1100 mg of glucosamine, 1200 mg of chondroitin, and 300 mg of MSM.
This glucosamine supplement is just slightly higher in price than the average bottle of glucosamine.
- Simple, once-a-day formula
- Smaller concentrations of main ingredients
10. Osteo Bi-Flex Triple Strength
This combination will not only increase joint mobility and comfort. It will also strengthen your joints with regular use. Users report a significant decrease in joint pain, but many reported needing to use a pain reliever in conjunction with this product or switching products altogether.
In addition to 1500 mg of glucosamine and 1100 mg of a chondroitin/MSM complex, this glucosamine supplement contains 100 mg of Joint Shield, which is a Boswellia serrata extract.
Osteo Bi-Flex Triple Strength glucosamine supplement is sold at the average price of other glucosamine supplements.
- Relieves pain and strengthens joints
- Does not contain separate amounts of chondroitin and MSM
So what happens when your body isn’t producing a sufficient amount of glucosamine? You hurt. A lot. And you will hurt specifically in your joints. Many medical professionals recommend taking a glucosamine supplement to help increase the amount of glucosamine in our bodies, which will help us reap all of the benefits that glucosamine brings, and allow us to move pain-free.
Glucosamine has been shown to lower inflammation, reduce joint pain and tenderness, and rebuild tissue and cartilage, among other benefits. It takes approximately 6 to 8 weeks for the glucosamine to truly begin having an effect on your pain and join health. There are many different brands of glucosamine on the market, and they come in many combinations. Below is a list of the ten best glucosamine supplements to help you choose which one will help you have a pain-free run.