10 Best Glucosamine Supplements Reviewed

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Our bodies produce a natural shock absorber and lubricant that helps us live active lives without experiencing contstant pain from friction. This natural shock absorber is glucosamine. Glucosamine is an amino sugar that is naturally found in our cartilage. Our bodies need glucosamine to synthesize protein and lipids to form important tissues, like cartilage, with the help of compounds like aggrecan and proteoglycans.

Schiff Move Free Advanced
  • Schiff Move Free Advanced
  • 4.8 out of 5
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  • 1500mg Glucosamine
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Doctor’s Best Glucosamine
  • Doctor’s Best Glucosamine
  • 4.6 out of 5
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  • 750mg Glucosamine
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Kirkland Glucosamine
  • Kirkland Glucosamine
  • 4.4 out of 5
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  • 1500mg Glucosamine
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It is an important component of our joints, tendons, and ligaments, and helps to form the fluids that provide lubrication to our joints. And as if glucosamine didn’t do enough for us already, it also contributes to our microbiome health by forming connective tissues that make up the digestive tract and help our immune system function at its highest level.

1. Schiff Move Free Advanced

Editor rating: 9.5 / 10
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This glucosamine supplement is a power-packed combination of glucosamine, chondroitin, MSM and hyaluronic acid. Just three of these tablets each day will chase your joint pain away.
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Effectiveness
Move Free Advanced is specially formulated to support the five signs of joint health: mobility, comfort, strength, flexibility, and lubrication. Users report that within one month of consistently taking the recommended dose of Move Free Advanced, they felt a significant reduction in joint pain, especially in their hips.

Dosage/Combination
Move Free Advanced glucosamine supplement contains: 1500 mg of glucosamine which supports the formation of cartilage and everyday mobility and flexibility, 200 mg of chondroitin to support joint strength, cushioning, and lubrication; 200 mg of a mineral compound called Uniflex that Move Free says will lessen pain within 2 weeks, 3.3 mg of hyaluronic acid, which helps support joint lubrication, and 1500 mg of MSM which is a source of sulfur related to collagen production.

Value
Move Free Advanced is about the average price for a glucosamine supplement.
Pros
  • Quick relief from pain
  • Includes compounds that occur naturally in the body
Cons
  • Must take 3 pills per day

2. Doctor’s Best Glucosamine

Editor rating: 9.0 / 10
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This non-GMO and gluten-free glucosamine supplement contains three ingredients that are proven to rebuild cartilage to keep your joints cushioned and pain-free when you run.
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Effectiveness
Users of Doctor’s Best Glucosamine say that this supplement starts to take affect after two weeks of consistent use. They also say that you must take the whole two-pill dose, or else you will begin feeling pain again almost immediately.

Dosage/Combination
A two-capsule dose of Doctor’s Best Glucosamine contains 750 mg of glucosamine sulfate, 600 mg of chondroitin sulfate, and 500 mg of MSM. This combination of ingredients has been shown to increase cartilage production and lubrication around joints, and decrease joint pain. Doctor’s Best Glucosamine is the only glucosamine supplement to contain OptiMSM, a specially-formulated blend of MSM created by Bergstrom Nutrition, which has been scientifically proven to improve joint, skin, and immune health.

Value
Doctor’s Best Glucosamine is a lower-priced glucosamine supplement.
Pros
  • GMO- and gluten-free
  • OptiMSM
Cons
  • Pain returns immediately upon not taking supplement

3. Kirkland Signature Extra Strength Glucosamine

Editor rating: 8.5 / 10
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This glucosamine supplement is a wholesale generic brand, but don’t let that fool you. It contains two ingredients that work together to fight pain caused by a lack of joint cushioning and lubrication. It does not contain chondroitin like many other glucosamine supplements do.
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Effectiveness
Two tablets of this glucosamine supplement will help your body produce extra collagen, which is an important component of your joints and connective tissue. Users reported that after a few weeks of use, joint pain, especially in the knees, was reduced. However, some users also reported having to discontinue use of this product due to increases in ocular pressure, which can lead to eye problems like glaucoma and vision loss.

Value:
Due to its wholesale size, this is one of the least expensive glucosamine supplements on the market.
Pros
  • Low price
  • Reported reduction in knee pain
Cons
  • May cause increases in ocular pressure

4. VitaBreeze Triple Strength

Editor rating: 8.0 / 10
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VitaBreeze Triple Strength incorporates turmeric into its glucosamine supplement formula for a unique added boost. Turmeric has been shown to be a very powerful antioxidant that has impressive anti inflammatory properties.
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Effectiveness
VitaBreeze guarantees that four of their gelatin-free Veggie Capsules will provide you with joint pain relief in 60 days, or they will refund your purchase. Users report greatly increased mobility, decreased pain, and that taking this supplement has nearly eliminated the use of OTC pain relievers from their joint pain management routine.

Dosage/Combination
Each dose of VitaBreeze Triple Strength is 4 capsules, and it is recommended that you take two, 2-pill doses daily. Each dose of this glucosamine supplement contains 1500 mg glucosamine, 1000 mg chondroitin, 600 mg MSM, and 300 mg turmeric.

Value
This is a higher priced glucosamine supplement.
Pros
  • Effective
  • Contains natural antioxidant/anti inflammatory turmeric
Cons
  • Expensive

5. Zenwise Labs Joint Support Pro-Mobility Formula

Editor rating: 7.5 / 10
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Zenwise labs created a glucosamine supplement to promote overall mobility. It combines glucosamine and two other movement-supporting supplements to help you run pain free. This glucosamine supplement also includes natural ingredients to help improve the effectiveness of its main ingredients.
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Effectiveness
After 28 days of taking this glucosamine supplement, one user with severe joint problems reporting comfort sleeping at night, and that there was no longer cracking or popping in the knees or shoulders.

Dosage/Combination
Two tablets of Zenwise Labs Joint Support Pro-Mobility Formula will give you 1500 mg of glucosamine, 1200 mg of chondroitin, and 1000 mg of MSM. This combination of medicines promotes joint and muscle flexibility as well as joint health.

Value
This glucosamine supplement is a little pricier than most others.
Pros
  • Takes effect in less than one month
  • Supplemental ingredients are natural
Cons
  • Higher price than most other supplements

6. Wellesse Joint Movement Glucosamine

Editor rating: 7.5 / 10
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This glucosamine supplement is unique in that it is a liquid formula. It also contains one of the highest concentrations of glucosamine of any supplement.
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Effectiveness
Users report that Wellesse Joint Movement Glucosamine doesn’t taste terrible, but it is overly sweetened with artificial sweeteners.

Dosage/Combination
One ounce per day, or tablespoons, of this glucosamine supplement will provide you with 2000 mg of glucosamine, 1200 mg of chondroitin, 500 mg of MSM, and 10 mg of hyaluronic acid. This liquid formula is made with no artificial ingredients or flavors.

Value
This glucosamine supplement is priced a little above average.
Pros
  • Easy-to-swallow
  • High concentration of glucosamine
Cons
  • Artificially sweetened taste

7. Universal Nutrition Animal Flex

Editor rating: 7.5 / 10
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Animal Flex glucosamine supplement is geared toward serious lifters. Taken once daily, this 8-time award winning glucosamine supplement will not only relieve your aches and pains, it will also help repair all of your joints, including your elbows, knees, and hips.
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Effectiveness
Users report some relief of joint pain and discomfort, but they also report side effects such as headaches, sinus pressure, and a racing heart.

Dosage/Combination
One serving of Animal Flex is one packet, and it must be taken with a meal. Animal Flex glucosamine supplement has three “Complexes”: Joint Construction, Joint Lubrication, and Joint Support. The Joint Construction Complex contains glucosamine, MSM, and chondroitin. The Joint Lubrication Complex contains flaxseed oil, a cetyl myristoleate proprietary blend, and hyaluronic acid. The Joint Support Complex contains ginger, turmeric, boswellic acid, quercetin, and bromelain.

Value
Animal Flex is a slightly higher priced glucosamine supplement.
Pros
  • Offers joint construction, support and lubrication
Cons
  • Potential side effects

8. Schiff Glucosamine

Editor rating: 7.0 / 10
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Schiff Glucosamine Plus MSM provides the highest potency of glucosamine for healthy joints and cartilage. It contains additional ingredients that also help with strength and lubrication.
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Effectiveness
Users report quick results with joint pain in hips and knees, and Schiff Glucosamine Plus MSM has even provided relief for pets.

Dosage/Combination
Three tablets once daily of this glucosamine supplement contain 1500 mg of glucosamine, 1500 mg of MSM, and 3 mg of hyaluronic acid. Together, these ingredients help relieve joint discomfort, promote lubrication, and increase cushioning. There is no chondroitin in this formula.

Value
This glucosamine supplement is priced slightly lower than others.
Pros
  • Quick relief
Cons
  • Does not contain chondroitin

9. NOW Foods Glucosamine

Editor rating: 6.5 / 10
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This glucosamine supplement, manufactured by NOW, contains three key ingredients to help combat joint pain and discomfort.
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Effectiveness
Users report that this product did help their joint pain, but the dosage had to be adjusted because it contains lesser concentrations of glucosamine, chondroitin, and MSM than some other glucosamine supplement formulas. It was recommended to users to calculate a new dosage based on their body weight.

Dosage/Combination
A three-capsule dose of NOW Foods Glucoosamine contains 1100 mg of glucosamine, 1200 mg of chondroitin, and 300 mg of MSM.

Value
This glucosamine supplement is just slightly higher in price than the average bottle of glucosamine.
Pros
  • Simple, once-a-day formula
Cons
  • Smaller concentrations of main ingredients

10. Osteo Bi-Flex Triple Strength

Editor rating: 6.0 / 10
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Osteo Bi-Flex Triple Strength promises increased joint comfort within in 7 days of using the product as recommended. Its secret weapon is an ingredient called Joint Shield.
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Effectiveness
This combination will not only increase joint mobility and comfort. It will also strengthen your joints with regular use. Users report a significant decrease in joint pain, but many reported needing to use a pain reliever in conjunction with this product or switching products altogether.

Dosage/Combination
In addition to 1500 mg of glucosamine and 1100 mg of a chondroitin/MSM complex, this glucosamine supplement contains 100 mg of Joint Shield, which is a Boswellia serrata extract.

Value
Osteo Bi-Flex Triple Strength glucosamine supplement is sold at the average price of other glucosamine supplements.
Pros
  • Relieves pain and strengthens joints
Cons
  • Does not contain separate amounts of chondroitin and MSM

So what happens when your body isn’t producing a sufficient amount of glucosamine? You hurt. A lot. And you will hurt specifically in your joints. Many medical professionals recommend taking a glucosamine supplement to help increase the amount of glucosamine in our bodies, which will help us reap all of the benefits that glucosamine brings, and allow us to move pain-free.

Glucosamine has been shown to lower inflammation, reduce joint pain and tenderness, and rebuild tissue and cartilage, among other benefits.  It takes approximately 6 to 8 weeks for the glucosamine to truly begin having an effect on your pain and join health. There are many different brands of glucosamine on the market, and they come in many combinations. Below is a list of the ten best glucosamine supplements to help you choose which one will help you have a pain-free run.